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SODIUM POTASSIUM CHLORIDE SYMPORTER INHIBITORS
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DeCS
Descriptor
English
:
Sodium Potassium Chloride Symporter Inhibitors
Descriptor
Spanish
:
Inhibidores del Simportador de Cloruro Sódico y Cloruro Potásico
Descriptor
Portuguese
:
Inibidores de Simportadores de Cloreto de Sódio e Potássio
Tree Number:
D27.505.519.562.906
D27.505.696.560.500.931
Definition
English
:
Agents that inhibit
SODIUM-POTASSIUM-CHLORIDE SYMPORTERS
which are concentrated in the thick ascending limb at the junction of the
LOOP OF HENLE
and
KIDNEY TUBULES
, DISTAL. They act as
DIURETICS
. Excess use is associated with
HYPOKALEMIA
and
HYPERGLYCEMIA.
History Note
English
:
2006
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
51201
Unique Identifier:
D049994
Occurrence in VHL
:
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DeCS
CID-10
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